Moorook is a settlement in South Australia. It is part of a series of towns surrounding lakes in the Riverland region in Australia. At the 2006 census, Moorook had a population of 289.
The town of Moorook was surveyed in April 1922 on the left bank of the Murray River where it flows north between Loxton and Kingston on Murray. Moorook is just downstream of Moorook Island and upstream of most of Moorook Game Reserve which surrounds and contains Wachtels Lagoon. Moorook had earlier been one of the experimental Village Settlements.
Moorook is a few kilometres south of the Sturt Highway and is a few kilometres northeast of the terminus of the former Moorook railway line.